{"id":2874,"date":"2021-11-12T16:20:40","date_gmt":"2021-11-12T15:20:40","guid":{"rendered":"https:\/\/genmico.unizar.es\/?page_id=2874"},"modified":"2023-02-22T11:31:08","modified_gmt":"2023-02-22T10:31:08","slug":"d2amr-antimicrobials","status":"publish","type":"page","link":"https:\/\/genmico.unizar.es\/en\/d2amr-antimicrobials\/","title":{"rendered":"D2AMR ANTIMICROBIALS"},"content":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243; css=&#8221;.vc_custom_1610458272385{margin-top: -24px !important;}&#8221;][vc_column_text]<\/p>\n<aside id=\"enhancedtextwidget-3\" class=\"widget-odd widget-3 widget widget_text enhanced-text-widget\">\n<h3 class=\"widget-title\">ANTIMICROBIALS<\/h3>\n<\/aside>\n<p>[\/vc_column_text][vc_wp_custommenu nav_menu=&#8221;33&#8243;][vc_single_image image=&#8221;2245&#8243; img_size=&#8221;medium&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;]<h2 style=\"text-align:left;font-size:24px;line-height:28px;\" class=\"tm-custom-heading \" >D2AMR: Discovery and development of antimicrobials and resistance mechanisms. PIs: Jos\u00e9 Antonio A\u00ednsa and Santiago Ram\u00f3n-Garc\u00eda<\/h2>\n[vc_column_text]One of the effective ways to deal with infectious diseases is through the administration of antimicrobial therapies, although the emergence of antimicrobial-resistant bacteria is jeopardizing this therapeutic option. The main lines of research of the D2AMR team include the characterization of mechanisms of intrinsic resistance to antimicrobials, discovery and pre-clinical development of bioactive compounds as new antimicrobials, repositioning of drugs with antimicrobial applications based on synergism, nanoparticles as antimicrobial drug carriers and the development of dynamic pharmacological models for the study of antimicrobial activity.<\/p>\n<p>Our research is mainly focused on M. tuberculosis, on non-tuberculous mycobacteria such as<em> M. abscessus, M. kansasii and M. ulcerans<\/em>, and on Gram-positive or Gram-negative bacteria with multiple resistance to antibiotics such as <em>Staphylococcus aureus, Streptococcus pneumoniae, Helicobacter pylori<\/em> and <em>KlebsielLa pneumoniae<\/em>, among others.[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243; css=&#8221;.vc_custom_1610458272385{margin-top: -24px !important;}&#8221;][vc_column_text] ANTIMICROBIALS [\/vc_column_text][vc_wp_custommenu nav_menu=&#8221;33&#8243;][vc_single_image image=&#8221;2245&#8243; img_size=&#8221;medium&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]One of the effective ways to deal with infectious diseases is through the administration of antimicrobial therapies, although the emergence of antimicrobial-resistant bacteria is jeopardizing this therapeutic option. The main lines of research of the D2AMR team include the characterization of mechanisms of intrinsic resistance &hellip; <a href=\"https:\/\/genmico.unizar.es\/en\/d2amr-antimicrobials\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">D2AMR ANTIMICROBIALS<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/pages\/2874"}],"collection":[{"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/comments?post=2874"}],"version-history":[{"count":8,"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/pages\/2874\/revisions"}],"predecessor-version":[{"id":3077,"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/pages\/2874\/revisions\/3077"}],"wp:attachment":[{"href":"https:\/\/genmico.unizar.es\/en\/wp-json\/wp\/v2\/media?parent=2874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}