Our Research Group of Mycobacterial Genetics has been working since 1992 in four lines of research financed by European and national investigation funds and that has permitted it to acquire an internationally recognized prestige. These lines of research include:

1 - Construction of New Vaccines against Tuberculosis

2 - Molecular Epidemiology of Tuberculosis

3 - Molecular Bases of the Resistance of mycobacteria

4 - Transposition and Latency of M. tuberculosis

The objectives of our group are to study the complexity of M. tuberculosis in a multidisciplinary focus and our group is coordinated with other national and international groups. More concretely we focus our research in:

 

1 - Genes implicated in the pathogenicity and virulence of M. tuberculosis

2 - Molecular epidemiology of tuberculosis, risk factors of transmission, and differences between strains of major epidemiological importance

3 - Mechanisms of resistance

4 - The mechanism of slow growth of the Koch bacillus

Active Projects

  • TBTEA Collaboration and integration of tuberculosis vaccine trials in Europe and Africa
    European Union Organization
    Chief Researcher and Coordinator: Carlos Martín Montañes

  • MM4TB More Medicines for Tuberculosis.
    European Union Organization
    Chief Researcher and Coordinator: José Antonio Ainsa

  • New TBVAC Discovery and preclinical testing of new vaccine candidates for tuberculosis
    European Union Organization
    Chief Researcher and Coordinator: Carlos Martín Montañes

  • BIO2011-23555 Project: “Study of the mechanisms of protection of MTBVAC and its potential use as recombinant polyvalent vaccine.”
    MCyT/DGI/FEDER Organization
    2012-2014
    Chief Researcher and Coordinator: Carlos Martín

  • BIO 2008 - 01561 Project: “Study of the virulence mechanisms regulated by PhoP in Mycobacterium tuberculosis. Application in the construction of new vaccines against tuberculosis”
    MCyT/DGI/FEDER Organization
    2009-2011
    Chief Researcher and Coordinator: Carlos Martín Montañes

  • Proyecto BIO2009-09405 Project: "Study of membrane transporters in Mycobacterium tuberculosis: implications in resistance and virulence".
    MCyT/DGI/FEDER Organization
    2010-2012
    Chief Researcher and Coordinator: José Antonio Ainsa

  • Agreement of collaboration between Genoma España and the University of Zaragoza for the development of the project “Vaccine against Tuberculosis”
  • Collaboration Agreement between the Government of Aragonand the University of Zaragoza.
    Molecular studies of tuberculosis..

  • Collaboration Agreement between Glaxo Smithkline Investigation and Development SL and the University of Zaragoza. Analysis and evaluation of antituberculous compounds.

  • OTRI Genetic Studies of Mycobacterium tuberculosis strains derived from an “x” area of the Community of Madrid, Autonomous Community of Galicia, General Hospital of Castellón and other Autonomous Communities.